A conditional hierarchy nauman faizi university of virginia introduction this essay is an attempt to study the manner in which averroes constructs the. Bleeding during treatment with aspirin versus apixaban in. Efficacy and safety of apixaban compared with aspirin in. Apixaban to prevent stroke in patients with atrial. Averroes argues that the attribute of life can be inferred because it is the precondition of knowledge and also because god willed objects into being. Download pdf the investigational factor xa inhibitor apixaban is superior to aspirin for the prevention of stroke in patients with atrial fibrillation af, and does not increase the risk of bleeding. Therefore, zur linde must repress feelings such as mercy or compassion, and nourish, instead, violence, murder, and destruction. Acetylsalicylic acid to prevent stroke in atrial fibrillation patients who have failed or are unsuitable for vitamin k antagonist treatment was a randomized doubleblind clinical trial which tested the efficacy and safety of apixaban, a new factor xa inhibitor, against aspirin for prevention of thromboembolism in af. Apixaban to prevent stroke in patients with atrial fibrillation. In a doubleblind study, we randomly assigned 5599 patients with atrial fibrillation who were at increased risk for stroke and for whom.
The 2011 apixaban versus acetylsalicylic acid to prevent stroke in atrial fibrillation patients who have failed or are unsuitable for vitamin k antagonist treatment averroes trial randomized 5,599 patients with af thought to be unsuitable candidates for vka therapy to apixaban or aspirin. The refutation of their theory of the incorruptibility of. He is best known for his commentaries on aristotle. Listing a study does not mean it has been evaluated by the u. Project muse an evaluation of averroes paraphrase on. Comparison of study designs and key findings of the averroes and aristotle trials connolly et al. Pdf apixaban in patients with atrial fibrillation researchgate. A phase iii study of apixaban in patients with atrial. Averroes retained from the aristotles thought the following points. Efficacy and safety of apixaban compared with aspirin in the. Apixabancalibrated antifxa activity in relation to outcome events. A previous history of stroke increases the annual risk of stroke from 45% to 117% in patients with nonvalvular atrial fibrillation. However, many patients are not suitable candidates for or are unwilling to receive vitamin k. The study will be stopped early because a predefined interim analysis by the independent data monitoring committee dmc revealed clear evidence of a.
Apixaban is a novel oral direct factor xa inhibitor that. Apixaban in patients with atrial fibrillation nejm. Averroes ibn rushd, influential islamic religious philosopher who integrated islamic traditions with ancient greek thought. Age and ageing oxford academic journals oxford university press. Bleeding during treatment with aspirin versus apixaban in patients.
Find, read and cite all the research you need on researchgate. Apixaban triumphs over aspirin for stroke prevention in. Jan garrett this page slightly revised december 4, 2007. Ibn rushd averroes is regarded by many as the foremost islamic philosopher. Commentaries by alexander of aphrodisias and by simplicius were frequent, but those by the arab averroes on the aristotelian works were ultimately the most influential. This stimulating book covers all area of the twelfth century muslim philosophers life from his transmission of aristotelian thought to the western world. Averroes is a doubleblind, doubledummy superiority trial of apixaban 5 mg twice daily 2. Downloaded from at hospital sirio libanes on march 2, 2011.
In a doubleblind study, we randomly assigned 5599 patients with atrial fibrillation. Averroes apixaban versus asa to prevent stroke in af patients who. Download fulltext pdf efficacy and safety of apixaban compared with aspirin in the elderly. Thus, a clear superiority of apixaban over aspirin was shown in terms of efficacy, with comparable safety. This subgroup analysis suggests that the absolute benefit of apixaban over aspirin might be enhanced in secondary stroke prevention. We compared the baseline characteristics and effects of apixaban compared with aspirin on clinical outcomes by age. Power can be inferred by gods ability to bring creations into existence.
A subgroup analysis from the averroes trial article pdf available in age and ageing 451. Averroes also argues that knowledge and power inevitably give rise to speech. His life, work and influence great islamic writings majid fakhry on. We will here briefly discuss the clinical implications of the trial. The averroes study has shown that apixaban was clearly superior to. This page is not for direct citation in scholarly work. In a doubleblind study, we randomly assigned 5599 patients with atrial fibrillation who were at. Averroes on the relationship between philosophy and scripture. Pdf efficacy and safety of apixaban compared with aspirin in the. Background vitamin k antagonists have been shown to prevent stroke in patients with atrial fibrillation. Apixaban in patients with atrial fibrillation eliquis.
The incoherence of the incoherence averroes ibn rushd etext conversion muhammad hozien. These lecture notes were created several years ago and have been only slightly modified recently. An evaluation of averroes paraphrase on aristotles poetics introduction it seems that aristotles poetics is a work which looms in the consciousness of critics of every age, and notably from the latter half of the sixteenth century onwards as critics become better practiced in their profession, they either consult this work or start to. Averroes synonyms, averroes pronunciation, averroes translation, english dictionary definition of averroes. Aristotle nct00412984 is a doubleblind, doubledummy, event driven phase iii trial testing noninferiority of apixaban 5 mg twice daily versus warfarin. Ibn rushd averroes 11261198 abu alwalid muhammad ibn ahmad ibn rushd, better known in the latin west as averroes, lived during a unique period in western intellectual history, in which interest in philosophy and theology was waning in the muslim world and just beginning to flourish in latin christendom. Pdf the effects of apixaban on hospitalizations in.
Averroes definition of averroes by medical dictionary. In brief, averroes was a prospective, multicentre, randomised trial of 5,599 patients with af conducted at 522 centres in 36 countries comparing apixaban with aspirin. The averroes trial 10 showed the superior efficacy of apixaban over aspirin without a significant increase in major bleeding complications in patients with atrial fibrillation. The rationale, design, definitions of outcomes, and main results of the averroes trial clinicaltrials. Pdf efficacy and safety of apixaban compared with aspirin. Installation of adobe acrobat pro dc trial by default uninstalls any earlier version of adobe acrobat on windows devices. The myth of the framework in borgess averroes search 151 logical narrative encourages ways of human behaviour while discouraging others. This quiz and worksheet duo can help you assess your knowledge of ibn rushds life and works.
Averroes definition of averroes by the free dictionary. A phase iii study of apixaban in patients with atrial fibrillation averroes the safety and scientific validity of this study is the responsibility of the study sponsor and investigators. The translations of the greek writings were normally accompanied by many greek and arabic commentaries. Pfe today announced that the companies have agreed to stop the phase 3 averroes clinical trial of apixaban in patients with atrial fibrillation.
The design and main results of the averroes trial have been published 10, 11. Averroes apixaban versus asa to prevent stroke in af. Averroes apixaban versus asa to prevent stroke in af patients who have failed or are unsuitable for vitamin k antagonist treatment trial n 5,599 included 1,898 patients. A conditional hierarchy nauman faizi university of virginia introduction this essay is an attempt. The myth of the framework in borgess averroes search. He wrote commentaries on plato and aristotle and defended philosophical study of religion against theologians such as alghazali, who had attacked muslim philosophers avicenna and alfarabi. Averroes nct00496769 was a randomised, doubleblind, doubledummy study to assess the superiority of apixaban 5 mg bid vs aspirin. Backgroundvitamin k antagonists are highly effective in preventing stroke in patients with atrial fibrillation but have several limitations. Ibn roschd, or averroes, as he was called by the latins, was educated in his native city, where his father and grandfather had held the office of cadi judge in civil affairs.
He was far more important and influential in jewish and christian thought than in islam. Abulwalid ibn rushd, better known as averroes 11261198, stands out as a towering figure in the history of arabislamic thought, as well as that of westeuropean philosophy and theology. Averroes was a doubleblind trial including 5599 patients from 36 countries who were at increased risk for stroke because of the presence of at least 1 risk factor in addition to atrial. Averroes on the relationship between philosophy and. And it is within this religious context that zur lindes statement. Concerning the eternity of the world the first proof the second proof the third proof the fourth proof the second discussion. Scribd is the worlds largest social reading and publishing site. If you choose to retain the existing acrobat xi on your machine, you need to change the default by unchecking the remove earlier version option in acrobat downloader ui. New anticoagulants and the future of cardiology revista.
In the islamic world, he played a decisive role in the defense of greek philosophy against the onslaughts of the as. Mar 25, 2011 download pdf the investigational factor xa inhibitor apixaban is superior to aspirin for the prevention of stroke in patients with atrial fibrillation af, and does not increase the risk of bleeding. Modification of outcomes with aspirin or apixaban in relation. The design, inclusion criteria, study execution, and main results of the averroes trial have been published. The averroes study was sponsored by bristolmyers squibb and pfizer. Efficacy and safety of apixaban compared with aspirin in the elderly. In this randomized, doubleblind trial, we compared apixaban at a dose of 5 mg twice daily with warfarin target international normalized ratio, 2. Ibn rushd averroes internet encyclopedia of philosophy.
932 1273 153 693 272 977 303 1191 1296 689 1246 1293 438 1090 1295 760 1225 501 93 523 299 1474 1199 450 1069 1272 1542 1465 138 1440 1198 607 1165 1562 531 16 885 758 130 639 79 507 988 128 1285